Figure 4. Annexin V-PI staining assessing 786-O and 786-O-R apoptosis rates after ubenimex treatment.

Ubenimex induced apoptosis in 786-O-R cells, an effect attenuated by the autophagy inhibitor 3MA, indicating a cross-talk between autophagy and apoptosis. (A) Flow-cytograms; (B) quantitation of a (*P < 0.05).