Figure 2. Effect of IGF-1R knockdown by RNAi on IGF-1R expression in Huh7 and Hep3B cells.
(A) IGF-1R mRNA level was significantly reduced in Huh7 and Hep3B cells with IGF-1R knockdown compared with the negative control or blank control. (B) IGF-1R protein level was lower in Huh7 and Hep3B cells with IGF-1R knockdown than that in the negative control or blank control group. (C) Representative western blot results of IGF-1R protein expression in Huh7 and Hep3B cells with IGF-1R knockdown and in the negative control or blank control group. **P < 0.01 versus negative control or blank control group. BL, blank control; NC, negative control; Si, IGF-1R siRNA.