Table 3. The genotype combinations of the SNP-SNP interaction in miR-199a rs74723057 and MET rs1621 with HCC risk.
Genotypes | Cases n | Controls n | Adjusted OR (95% CI)a | Pb | |
---|---|---|---|---|---|
miR-199a rs74723057 | MET rs1621 | ||||
GG+CG | AA + AG | 941 | 972 | reference | |
GG | 6 | 10 | 0.15 (0.03~0.73) | 0.018 | |
CC | AA + AG | 83 | 76 | reference | |
GG | 2 | 2 | 0.76 (0.04~14.02) | 0.85 |
Note: HCC, hepatocellular carcinoma; OR, odds ratio; CI, confidence interval.
Adjusted for age, sex, smoking status, alcohol use and HBV infection
P-value for interaction