Table 6. The multiple drug design for preventing the progression of HCC from stage II and stage III based on the progression mechanism in Figure 7.
Drug molecule | Target gene |
---|---|
celecoxib | DDIT3 |
axitinib | PDGFB |
vinblastine | JUN |
Multiple drug molecules | |
The multiple drug molecules comprise celecoxib, axitinib, and vinblastine for preventing HCC from stage II to stage III. The structure of these drug molecules based on ZINC database is shown in the following figure.