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. 2016 Oct 25;7(48):79596–79604. doi: 10.18632/oncotarget.12865

Table 3. Genetic polymorphisms and outcome - univariate associations with LSCC prognosis.

SNP-ID genotype N(Total/Events) Median P-valuea HR (95% CI) P-valueb
rs17401966 A/A 125/73 48.0 1
G/A 36/19 66.0 0.437 0.905 (0.545 - 1.502) 0.669
G/G 8/7 35.0 1.576 (0.724 - 3.430) 0.252
rs4072037 A/A 16394 46 1
G/A 2/2 81 0.843 0.976 (0.239 - 3.985) 0.973
G/G 3/3 59 1.403 (0.442 - 4.450) 0.565
rs1912453 T/T 41/25 46 1
C/T 113/65 62 0.389 0.936 (0.589 - 1.486) 0.779
C/C 15/10 35 1.489 (0.712 - 3.116) 0.290
rs10911251 C/C 45/28 36 1
A/C 81/48 59 0.720 0.831 (0.518 - 1.333) 0.443
A/A 34/19 66 0.949 (0.530 - 1.700) 0.860
rs6687758 A/A 114/68 59 1
G/A 44/26 44 0.979 1.047 (0.664 - 1.651) 0.842
G/G 5/2 34 0.975 (0.238 - 4.000) 0.972
rs11903757 T/T 156/88 59 1
C/T 14/12 23 0.021* 2.001 (1.091 - 3.673) 0.025*
C/C −/−
rs9288520 G/G 92/52 48 1
A/G 72/45 50 0.786 1.085 (0.727 - 1.619) 0.691
A/A 4/2 22 0.692 (0.166 - 2.877) 0.613
rs966423 C/C 111/65 62 1
T/C 52/29 44 0.000* 1.089 (0.701 - 1.690) 0.705
T/T 4/4 5 7.721(2.748 - 21.695) 0.000*
rs6736997 C/C 105/66 44 1
A/C 64/33 62 0.540 0.878 (0.577 - 1.336) 0.543
A/A −/−
rs975334 T/T 125/74 48 1
C/T 42/25 46 0.584 1.017 (1.017 - 1.603) 0.941
C/C 3/1 59 0.373 (0.052 - 2.687) 0.328
rs8180040 T/T 51/32 44 1
A/T 51/28 62 0.754 0.836 (0.501 - 1.394) 0.493
A/A 43/24 62 0.858 (0.505 - 1.458) 0.572
rs9841504 G/G 132/77 56 1
G/C 26/16 40 0.680 1.120 (0.652 - 1.925) 0.682
C/C 3/2 26 1.763 (0.430 - 7.223) 0.431
rs10936599 C/C 48/34 44 1
T/C 73/37 62 0.153 0.635 (0.398 - 1.014) 0.057
C/C 47/28 36 0.818 (0.494 - 1.356) 0.436
rs2239612 C/C 101/54 71 1
T/C 45/31 40 0.192 1.488 (0.954 - 2.321) 0.080
T/T 12/8 44 1.332 (0.632 - 2.810) 0.451
a

Notes: P-values based on the log-rank test;

a

P-values based on the Wald test;

*

p-value < 0.05 indicates statistical significance.

Abbreviations: HR, hazard ratios; CI: confidence intervals.