Figure 5. Analysis of the impact of the expression of Lin28A or Lin28B on the tumor stages and prognosis of colon cancer patients.
A. Neither Lin28A nor Lin28B protein expression is significantly different among different tumor size stages. B. The protein level of Lin28B but not Lin28A is significantly higher in patients with lymph node metastasis (N1 but not N2) than patients with non-lymph node metastasis (N0) (P<0.05). C. Neither Lin28A nor Lin28B mRNA level is significantly different among different tumor size stages. D. The mRNA level of Lin28A but not Lin28B is significantly higher in patients with lymph node metastasis (N1 but not N2) than patients with non-lymph node metastasis (N0) (P<0.01). E. The mRNA level of Lin28A instead of Lin28B in colon cancer patients with remote organ metastasis is significantly higher than that of patients with non-metastasis (P<0.05). F. The mRNA level of either Lin28A or Lin28B is not associated with the prognosis of colon cancer patients.