Figure 7. Both Lin28A and Lin28B promote the proliferation of HCT116 cells.
A. Both of Lin28A and Lin28B promote the proliferation of HCT116 cells detected by cell growth curve assay (*: P<0.05; **: P<0.01). B and C. Both of Lin28A and Lin28B promotes the proliferation of HCT116 cells detected by clone formation assay (**: P<0.01). D. The cell cycle assay demonstrated that Lin28A promotes the transition of cell cycle from S phase to G2/M phase, whereas Lin28B facilitates the transition of cell cycle from both G1 phase to S phase and S phase to G2/M phase.