Skip to main content
. 2016 Oct 27;7(48):79736–79746. doi: 10.18632/oncotarget.12945

Figure 7. A schematic diagram of GPC5 based signaling circuit in lung adenocarcinoma.

Figure 7

The diagrammatic process of regulating the Wnt/β-catenin signaling pathway and downstream effector proteins. In lung adenocarcinoma cells, GPC5 inhibits Epithelial-Mesenchymal Transition (EMT) by competitively binding to Wnt3a.