Table 1. Cell cycle distribution after treatment of Cos, Dehy, C+2D or VOSL for 48 h.
Cell lines | Treatment | Concentration | G0/G1 (%) | S (%) | G2/M (%) |
---|---|---|---|---|---|
SMMC-7721 | Control | 63.22±2.62 | 28.57±1.97 | 8.21±0.67 | |
Cos | IC10 | 59.43±0.62 | 33.85±0.59 * | 6.72±1.00 | |
IC30 | 50.71±0.73 ** | 39.44±0.60 ** | 9.86±0.15 | ||
IC50 | 41.77±0.30 *** | 51.01±0.22 *** | 7.22±0.33 | ||
Dehy | IC10 | 62.88±0.37 | 30.84±0.61 | 6.28±0.48 | |
IC30 | 55.57±0.83 ** | 35.89±0.66 * | 8.54±1.30 | ||
IC50 | 49.44±0.90 * | 46.22±0.94 *** | 4.34±1.18 *** | ||
C+2D | IC10 | 63.91±1.52 | 31.25±0.89 | 4.84±1.23 * | |
IC30 | 53.26±0.39 ** | 37.86±0.94 ** | 8.88±0.84 | ||
IC50 | 45.62± 0.72 *** | 48.57±0.45 *** | 5.80±1.09 * | ||
VOSL | IC10 | 62.67±1.55 | 29.84±0.70 | 7.42±0.96 | |
IC30 | 57.99±1.69 * | 34.09±0.29 ** | 7.91±1.96 | ||
IC50 | 54.96±1.68 ** | 41.12±1.45 *** | 3.92±0.46 * | ||
Hep3B | Control | 67.44 ±1.35 | 24.45±1.18 | 8.11±0.30 | |
Cos | IC10 | 65.85±3.14 | 25.41±1.06 | 8.74±3.29 | |
IC30 | 59.54±1.29 ** | 34.35±2.23 ** | 6.11±2.82 | ||
IC50 | 49.71±2.09 *** | 46.93±1.29 *** | 3.36±2.05* | ||
Dehy | IC10 | 64.47±3.62 | 26.14±0.86 | 9.40±3.25 | |
IC30 | 60.16±2.34 ** | 36.01±2.16 ** | 3.83±2.92 | ||
IC50 | 34.83±1.74 *** | 46.90±1.08 *** | 18.27±1.77 *** | ||
C+2D | IC10 | 64.88±2.14 | 29.31±0.67 ** | 5.81±2.19 | |
IC30 | 44.51±3.00 *** | 36.22±0.95 *** | 19.27±2.10 *** | ||
IC50 | 32.72±0.82 *** | 48.73±1.15 *** | 18.54±1.46 *** | ||
VOSL | IC10 | 53.43±0.74 *** | 27.92±1.65 * | 18.65±1.03 *** | |
IC30 | 57.56±1.68 ** | 35.11±1.67 *** | 7.34±1.63 | ||
IC50 | 33.55±0.64 *** | 43.78±1.25 *** | 22.68±1.48*** |
Note:
p < 0.05,
p < 0.01 and
p < 0.001 compared with the corresponding control group.