Table 3. Multivariate survival analyses of patients with stage II and stage IIIA rectal cancer from the SEER database.
| Variable | Multivariate analysis | P value | |
|---|---|---|---|
| HR | 95% CI | ||
| Age at diagnosis (yrs) | <0.001 | ||
| ≤70 | 1 | reference | |
| >70 | 1.686 | 1.572-1.807 | |
| Race | <0.001 | ||
| White | 1 | reference | |
| Black | 1.450 | 1.283-1.639 | <0.001 |
| Other a | 0.767 | 0.671-0.877 | <0.001 |
| Histological Type | 0.009 | ||
| Adenocarcinoma | 1 | reference | |
| Mucinous adenocarcinoma | 1.195 | 1.054-1.355 | 0.006 |
| Signet-ring cell carcinoma | 1.492 | 0.823-2.704 | 0.187 |
| Grade of differentiation | <0.001 | ||
| Well/Moderate | 1 | reference | |
| Poor/Undifferentiated | 1.207 | 1.095-1.329 | |
| Tumor size (cm) | 1.022 | 1.014-1.031 | <0.001 |
| LNH | <0.001 | ||
| <12 | 1 | reference | |
| ≥12 | 0.723 | 0.670-0.779 | |
| TNM stage | 0.001 | ||
| IIIA | 1 | reference | |
| II | 1.195 | 1.079-1.324 | |
HR = hazard ratio, CI = confidence interval, LNH = number of lymph nodes harvested.
a
Includes Native American, Asian, Pacific Islander and Unknown.