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. 2016 Nov 4;7(48):79914–79924. doi: 10.18632/oncotarget.13107

Figure 5. IL-13 induces chromatin remolding at the IL-10 promoter locus in B cells.

Figure 5

A-E., the levels of HDAC11 (A), acetylated H3K9 (B), Pol II (C), related transcription factors of IL-10 (D) and STAT3 (E) at the IL-10 promoter locus. F., IL-10 mRNA levels in B cells. The peripheral B cells were obtained from 18 healthy subjects and 6 FA patients. B cells were treated in the culture as denoted on the X axis for 16 h (A-C, E-F). LPS (100 ng/ml). IL-13 (100 ng/ml). *, p<0.01, compared to the saline group. #, p<0.01, compared to the LPS alone group. $, p<0.01, compared to the healthy group.