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. 2016 Nov 7;7(48):79943–79955. doi: 10.18632/oncotarget.13161

Figure 3. Kaplan-Meier analysis of PD-L1 DNA methylation in prostate cancer patients (training cohort).

Figure 3

A. Data for five beads from the Illumina Infinium Human Methylation 450 Bead Chip located in the PD-L1 Gene. Patient samples were stratified into mPD-L1low (grey) and mPD-L1high (black) using an optimized cut-off. Kaplan-Meier analysis of PD-L1 DNA methylation showed a better prognosis for the mPD-L1low subgroup according to the bead pairs cg15837913 and cg19724470. B. Univariate Cox proportional hazard analyses conducted using an optimized cut-off corroborated the prognostic value of mPD-L1.