Table 1. Association and correlation of PD-L1 DNA methylation with mRNA expression and BCR-free survival.

Bead	Correlation with mRNA ( ρ, p-value)	Cox (HR, [95%CI], p-value)†	Optimized cut-off [%]	Cox (HR, [95%CI], p-value)
cg15837913	−0.061, 0.17	1.01 [95%CI: 0.99-1.03], p = 0.29	35.845	2.07 [95%CI: 1.19-3.59], p = 0.010
cg02823866	0.084, 0.060	0.97 [95%CI: 0.61-1.54], p = 0.89	3.67	1.12 [95%CI: 0.51-2.47], p = 0.79
cg40305799	0.057, 0.21	0.78 [95%CI: 0.31-1.96], p = 0.59	1.764	0.68 [95%CI: 0.40-1.16], p = 0.15
cg13474877	0.032, 0.48	0.96 [95%CI: 0.87-1.07], p = 0.47	4.583	0.68 [95%CI: 0.32-1.45], p = 0.32
cg19724470	−0.160, <0.001	1.02 [95%CI: 1.00-1.04], p = 0.024	52.75	2.60 [95%CI: 1.50-4.51], p = 0.001

^†mPD-L1 analyzed as continuous variable