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. 2017 Mar 13;5:30. doi: 10.1186/s40168-017-0246-x

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Effect of cardiovascular disease interventions on the host serum metabolome. Serum metabolome OPLS-DA: a PSE (green) vs. HFC (red). b OBG (green) vs. HFC (red). c BSH (red) vs. HFC (green). d STAT (green) vs. HFC (red). Significant differences in e amino acids and biogenic amines, f acylcarnatines, and g phosphotidylcholines in serum from each group, as analyzed by DI and LC-MS/MS. *(p < 0.05) and **(p < 0.01) represent significant differences when compared against HFC in one-way ANOVA. Plots depict individual replicates with mean and SEM