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. 2017 Mar 13;10:131. doi: 10.1186/s13071-017-2074-z

Table 2.

Relationship between histopathological examination of spleen tissue samples and vector-borne pathogens detected

Dog PCR result Sample Hystopathology
S1 Babesia canis Frozen spleen HSA
S2 Babesia canis EDTA-blood HSA
S3 Babesia canis EDTA-blood HSA
S4 Babesia canis EDTA-blood HSA
S5 Babesia gibsoni Paraffin-fixed spleen EH, hemosiderosis, LNH
S6 Babesia gibsoni EDTA-blood Congestion, hematoma
S7 Babesia gibsoni EDTA-blood Congestion
C1 Babesia gibsoni EDTA-blood na
S8 “Babesia vulpes” EDTA-blood na (splenic torsion)
S9 Ehrlichia canis Frozen spleen Congestion, hematoma
C2 Hepatozoon canis EDTA-blood na
S10 Leishmania infantum Frozen spleen EH, myeloid metaplasia
S11 Candidatus Mycoplasma hemovis” EDTA-blood Congestion, EH, hemosiderosis
S12 Mycoplasma ovis EDTA-blood Carcinoma
S13 Rickettsia massilliae EDTA-blood LNH

Abbreviations: S, dogs with spleen alterations, C, control dogs, EH extramedullary hematopoiesis, HSA hemangiosarcoma, LNH lymphoid nodular hyperplasia, na not available