. 2016 Dec 22;83(4):855–862. doi: 10.1111/bcp.13169

Table 1.

British National Formulary‐recommended maximum daily doses for mefenamic acid, ibuprofen, diclofenac and naproxen, and the toxic doses for each drug as defined on TOXBASE®. Note: The maximum daily dose for any given indication for a drug was used

	Maximum daily dose		Toxic dose (mg kg ⁻¹ )
	Adults (mg)	Children	Toxic dose (mg kg ⁻¹ )
Mefenamic acid	1500	• Less than 12 years: not licensed • 12–18 years: 1500 mg	40
Ibuprofen	2400	• 1–3 months: 20 mg kg⁻¹ • 3 months‐12 years: 30 mg kg⁻¹ • 12–18 years: 2400 mg	100
Diclofenac	150	• 6 months–18 years: 5 mg kg⁻¹	7
Naproxen	1250	• 1 month–2 years: 15 mg kg⁻¹ • 2–18 years 10 mg kg⁻¹	35