Table 2.
Frequency distributions of CYP2C9, VKORC1, CYP4F2, POR*28, and PORrs286 polymorphisms in the current patient population
| SNP | Allele frequencies | Genotype frequencies | Hardy–Weinberg equilibrium test (P value) | |||
|---|---|---|---|---|---|---|
| CYP2C9 (rs1057910) | *1 (97.2%) | *3 (2.8%) | *1/*1249 (94.3%) | *1/*3 15(5.7%) | *3/*3 0(0%) | 0.635 |
| VKORC1 (rs9923231) | G (8.9%) | A (91.1%) | GG 1(0.4%) | GA 45(17.0%) | AA 218 (82.6%) | 0.407 |
| CYP4F2 (rs2108622) | C (75.0%) | T (25.0%) | CC 148(56.1%) | CT 100(37.8%) | TT 16(6.1%) | 0.870 |
| POR*28 (rs1057868) | C (66.7%) | T (33.3%) | CC 108(40.9%) | CT 136(51.5%) | TT 20(7.6%) | 0.010 |
| PORrs286 (rs2868177) | G (44.5%) | A (55.5%) | GG 51(19.3%) | GA 133(50.4%) | AA 80 (30.3%) | 0.747 |