Table 1.
Demographic, clinical, and outcome characteristics of 3813 stroke patients by hyperlipidemia statin use status
| Characteristics | no-HLD/no-statins (n = 860) |
HLD/no-statins (n = 830) |
HLD/on-statins (n = 2123) |
|---|---|---|---|
| Age (years) | |||
| Mean ± SD | 72.0 ± 17.4 | 70.3 ± 14.9† | 69.1 ± 13.1† |
| Median (25%–75% IQR) | 77.0 (60.0–85.0) | 72.5 (60.0–82.0) | 70.0 (59.0–79.0) |
| Sex (female), n (%) | 550 (64.0) | 463 (55.8)† | 1132 (53.3)† |
| Race (black), n (%) | 171 (19.9) | 161 (19.4) | 461 (21.7) |
| Body mass index, n (%) | |||
| Normal weight | 353 (41.1) | 262 (31.6)† | 576 (27.1)†‡ |
| Overweight | 217 (25.2) | 249 (30.0) | 654 (30.8)† |
| Obese | 144 (16.7) | 217 (26.1)† | 687 (32.4)†‡ |
| Smoking, n (%) | |||
| Never | 479 (55.7) | 393 (47.4)† | 952 (44.8)† |
| Former | 210 (24.4) | 215 (25.9) | 583 (27.5) |
| Current | 171 (19.9) | 222 (26.7)† | 588 (27.7)† |
| History, n (%) | |||
| Hypertension | 618 (71.9) | 708 (85.3)† | 1924 (90.6)†‡ |
| Diabetes mellitus | 226 (26.3) | 279 (33.6)† | 888 (41.8)†‡ |
| Atrial fibrillation | 197 (22.9) | 192 (23.1) | 375 (17.7)†‡ |
| Heart disease | 285 (33.1) | 334 (40.2)† | 993 (46.8)†‡ |
| Prior stroke | 213 (24.8) | 186 (22.4) | 590 (27.8)‡ |
| Family history of stroke | 93 (10.8) | 157 (18.9)† | 438 (20.6)† |
| Depression | 178 (20.7) | 191 (23.0) | 462 (21.8) |
| Dementia | 161 (18.7) | 101 (12.2)† | 194 (9.1)†‡ |
| Medication use | |||
| Antiplatelet | 637 (74.1) | 685 (82.5)† | 1941 (91.4)†‡ |
| Antithrombotic | 248 (28.8) | 239 (28.8) | 595 (28.0) |
| Baseline NIHSS | |||
| Median, (25%–75% IQR) | 4.0 (1.0–8.0) | 3.0 (1.0–6.0)† | 3.0 (1.0–6.0)† |
| Prestroke mRS, n (%) | |||
| (0–2) | 523 (60.8) | 572 (68.9)† | 1600 (75.4)†‡ |
| Mortality, n (%) | |||
| 30 days | 128 (14.9) | 70 (8.4)† | 93 (4.4)†‡ |
| 3 month | 181 (21.1) | 114 (13.7)† | 183 (8.6)†‡ |
| 3 year | 399 (46.4) | 311 (37.5)† | 617 (29.1)†‡ |
†
p < 0.05 versus no-HLD/no-statins group.
‡
p < 0.05 versus HLD/no-statins group.