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. 2017 Feb;58(1):40–48. doi: 10.3325/cmj.2017.58.40

Table 1.

Characteristics, treatment, and clinical outcomes in all patients with diffuse large B cell lymphoma (DLBCL) and a subgroup of DLBCL patients planned to receive autologous stem cell transplantation (ASCT)*

No. of DLBCL patients
Characteristics total (n = 75) planned to receive ASCT (n = 24)
Sex (male/female) 42/33 12/12
Age (years; median, IQR) 61 (47-71) 50 (41-57)
Ann Arbor III & IV 61 21
High LDH 57 21
ECOG≥2 26 11
>1 extranodal presentation 37 12
Bulky disease 28 11
Ki-67 ≥ 80% 31 8
Ki-67 ≥ 90% 18 7
B symptoms 37 15
IPI≥2 64 20
Age-adjusted IPI≥2 - 18
R-IPI poor risk 45 12
R-DA-EPOCH cycles (median, IQR) 6 (6-8) 7 (6-7)
ASCT transplantation 17 17
CD34+ cells mobilized with EPOCH - 18/21†
Irradiation 7 2

*Abbreviations: IQR – interquartile range; LDH – lactate dehydrogenase; ECOG – Eastern Cooperative Oncology Group; B symptoms – fever, weight loss, and night sweats; IPI –International Prognostic Index; R-IPI – revised IPI; R-DA-EPOCH – rituximab plus dose-adjusted regimen combining etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin.

Three patients planned to receive ASCT died prior to stem cell mobilization.