FIG. 4.

The mandibular defects treated with both BMP-2 (2.5 μg) and phenamil (300 μM) revealed the enhanced expression of osteogenic markers as early as 10 days postoperatively. (A, B) Runx2 and OCN were, respectively, assessed with immunohistochemical staining. (C, D) Semiquantitative analysis of Runx2 and OCN staining using ImageJ software. Images were taken at 40× magnification. Scale bar = 50 μm. Data presented as mean ± SD (n = 3/group). *p < 0.05, **p < 0.01. Color images available online at www.liebertpub.com/tea