FIG. 6.

Histological analysis of bone regeneration in mandibular defects treated with BMP-2 and phenamil. (A, B) Histological staining of mandibular defects treated with Ap-PLGA scaffolds loaded with BMP-2 and phenamil at 8 weeks postoperatively. Arrowhead indicates new bone tissues. Area within the black box indicates the high magnification of image below. Black arrowhead indicates new bone formation. Images were taken at 4× magnification for top image and 40× magnification for bottom image. Top scale bar = 500 μm, Bottom scale bar = 50 μm. (C) Masson's trichrome staining. Images were taken at 4× magnification, scale bar = 500 μm. (D) Sirius red staining at polarized light. Images were taken at 4× magnification. Scale bar = 500 μm. Color images available online at www.liebertpub.com/tea