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Hematoxylin and eosin staining of treated mouse skin after 30 days. Three-dimensional MA-HA maintained its macroporous ultrastructure 30 days after injection and showed signs of cellularization. The overall skin architecture was not adversely altered by either treatment. Upper panel: subcutaneous tissues above the panniculus carnosus; bottom panel: subcutaneous tissues below the panniculus carnosus. Scale bar represents 400 μm.
