Table 2.
GO Term Analysis for “Molecular Functions”
| GO term | GO term ID | p-Value |
|---|---|---|
| Upregulated genes | ||
| Binding | GO:0005488 | 4.94E-37 |
| Protein binding | GO:0005515 | 6.38E-24 |
| Nucleic acid binding transcription factor activity | GO:0001071 | 3.98E-18 |
| Sequence-specific DNA binding transcription factor activity | GO:0003700 | 1.45E-17 |
| Ion binding | GO:0043167 | 7.25E-17 |
| Metal ion binding | GO:0046872 | 1.79E-16 |
| Cation binding | GO:0043169 | 2.25E-16 |
| Sequence-specific DNA binding | GO:0043565 | 3.90E-16 |
| Carbohydrate derivative binding | GO:0097367 | 8.51E-12 |
| Calcium ion binding | GO:0005509 | 1.55E-11 |
| Glycosaminoglycan binding | GO:0005539 | 3.91E-11 |
| DNA binding | GO:0003677 | 1.25E-10 |
| Sulfur compound binding | GO:1901681 | 1.30E-09 |
| Identical protein binding | GO:0042802 | 1.16E-08 |
| Chromatin binding | GO:0003682 | 2.18E-08 |
| Growth factor binding | GO:0019838 | 2.32E-08 |
| Heparin binding | GO:0008201 | 5.35E-08 |
| Receptor binding | GO:0005102 | 6.70E-08 |
| Extracellular matrix structural constituent | GO:0005201 | 1.13E-07 |
| Extracellular matrix binding | GO:0050840 | 1.74E-07 |
| Downregulated genes | ||
| Protein binding | GO:0005515 | 2.08E-26 |
| Binding | GO:0005488 | 2.14E-26 |
| Calcium ion binding | GO:0005509 | 1.31E-16 |
| Actin binding | GO:0003779 | 1.34E-10 |
| Cytoskeletal protein binding | GO:0008092 | 2.79E-09 |
| Ion binding | GO:0043167 | 1.73E-07 |
| Receptor binding | GO:0005102 | 3.08E-07 |
| Phospholipid binding | GO:0005543 | 6.96E-07 |
| Lipid binding | GO:0008289 | 8.23E-07 |
| Structural molecule activity | GO:0005198 | 1.07E-06 |
| S100 protein binding | GO:0044548 | 3.42E-06 |
| Anion binding | GO:0043168 | 8.43E-06 |
| Transporter activity | GO:0005215 | 1.41E-05 |
| Identical protein binding | GO:042802 | 2.99E-05 |
| Chemokine receptor binding | GO:0042379 | 4.62E-05 |
| Chemokine activity | GO:0008009 | 4.89E-05 |
| Actin filament binding | GO:0051015 | 6.15E-05 |
| Immunoglobulin binding | GO:0019865 | 6.73E-05 |
| Transmembrane transporter activity | GO:0022857 | 8.18E-05 |
| Protein complex binding | GO:0032403 | 9.45E-05 |