Figure 6.

Wound healing in streptozotocin-induced diabetic mice treated with α-gal nanoparticles. (A) Control wound treated for 12 days with saline. No significant regenerating epidermis (H&E). (B) A wound treated for 12 days with 10 mg α-gal nanoparticles. The border of the wound (wound bed) is indicated by the intact dermis in the left area. The wound is completely covered with regenerating epidermis (H&E). (C, D) Trichrome staining of sections (A) and (B), respectively. The collagen in the wound bed is stained in the left area as deep blue. Representative mice of five diabetic mice/group (100 × ). To see this illustration in color, the reader is referred to the web version of this article at www.liebertpub.com/wound