Table 1.
Baseline demographic and clinical variables for all patients included and for the subgroups that were observed for 2 and 6 years, respectively
Variables | Baseline (n = 122) (1) | Dropped out after 2 years (n = 41) (2) | Followed up for 6 years (n = 81) (3) | ANOVA p value | Post hoc p values (Tukey) |
---|---|---|---|---|---|
Mean age, years | 62.5 (7.9) [45–79] | 65.3 (8.2) [48–79] | 61.0 (7.5) [45–78] | 0.02 | 1 vs. 2 = 0.11 ns 1 vs. 3 = 0.41 ns 2 vs. 3 = 0.01** |
Education, years | 12.5 (3.3) [6–20] | 13.0 (3.7) [6–20] | 12.3 (3.1) [6–18] | 0.47 | ns |
GDS | 2.5 (0.5) [1–3] | 2.5 (0.5) [1–3] | 2.5 (0.5) [1–3] | 0.20 | ns |
MMSE | 28.8 (1.1) [25–30] | 29.1 (1.0) [27–30] | 28.7 (1.2) [25–30] | 0.97 | ns |
T-tau, ng/L | 302.4 (173.3) [79–1,090] | 325.1 (218.9) [90–1,090] | 291.0 (145.5) [79–660] | 0.77 | ns |
P-tau, ng/L | 55.1 (23.6) [22–188] | 52.9 (31.5) [22–188] | 56.3 (18.6) [24–100] | 0.60 | ns |
Aβ42, ng/L | 686.2 (242.4) [160–1,507] | 650.2 (232.0) [220–1,140] | 704.2 (246.9) [160–1,507] | 0.52 | ns |
T-tau/Aβ42 ratio | 0.54 (0.52) [0.07–3.76] | 0.63 (0.73) [0.16–3.78] | 0.49 (0.37) [0.07–1.68] | 0.36 | ns |
Females, n (%) | 67 (54.9) | 24 (58.5) | 43 (53.1) | X2 | ns |
Values in parentheses are SD, and values in square brackets are ranges, unless otherwise indicated. ns, nonsignificant.
p ≥ 0.01.