Table 4.
Baseline characteristics and cognitive change over 2 years from baseline of the patients who developed dementia versus patients with only SCI or MCI after 6 years
| Demented (n = 4) | SCI/MCI (n = 77) | p value | |
|---|---|---|---|
| Baseline characteristics | |||
| Age, years | 62.0 (7.0) | 61.0 (7.5) | 0.79 |
| Education, years | 13.0 (4.7) | 12.2 (3.0) | 0.66 |
| MMSE | 27.8 (1.0) | 28.7 (1.2) | 0.11 |
| P-tau, ng/L | 58.3 (29.9) | 56.2 (18.3) | 0.85 |
| T-tau, ng/L | 223.3 (110.7) | 294.6 (146.8) | 0.34 |
| Aβ42, ng/L | 408.0 (150.0) | 719.8 (241.6) | 0.01** |
| T-tau/Aβ42 ratio | 0.63 (0.4) | 0.48 (0.4) | 0.44 |
| Average Memory T score | 49.4 (4.0) | 54.8 (7.5) | 0.16 |
| Average Executive T score | 46.5 (7.8) | 53.4 (5.9) | 0.02* |
| Cognitive change over 2 years from baseline | |||
| Average Memory T-score change | -8.4 (8.1) | +1.2 (8.1) | 0.02* |
| Average Executive T-score change | -1.3 (4.9) | +1.2 (5.6) | 0.40 |
Values in parentheses are SD.
*
p ≥ 0.05
**
p ≥ 0.01.