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| Enzyme | Substrate | Control Inhibitor (IC50 (μM)) | Cmpd 36 IC50 (μM) |
|---|---|---|---|
| CYP1A2 | Phenacetin | Furafylline (6.29) | 58.6 |
| CYP2C8 | Paclitaxel | Quercetin (1.20) | 7.9 |
| CYP2C9 | Tolbutamide | Sulfaphenazole (0.205) | 8.5 |
| CYP2C19 | S-Mephentoin | Tranylcypromine (10.3) | 20.0 |
| CYP2D6 | Bufuralol | Quinidine (0.035) | 148 |
| CYP3A4 | Midazolam | Ketoconazole (0.018) | 81.9 |
| CYP3A4 | Testosterone | Ketoconazole (0.015) | 12.5 |
