Figure 1.

(A) Chemical structure of QL47. (B) Huh7 cells were infected with DENV2 then treated with a range of QL47 concentrations. Cell viability (black) and viral yield (red) were measured 24 hours later. CC₅₀ and IC₉₀ values—respectively, corresponding to the concentrations of QL47 that lead to 50% cytotoxicity and to a 1-log₁₀ unit reduction in the number of infectious progeny virions produced—were determined by non-linear regression. Representative data (mean ± standard deviation of experimental duplicates) out of n ≥ 2 repeats are shown.