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. 2017 Mar 10;8(2):337–350. doi: 10.3945/an.116.014209

FIGURE 1.

FIGURE 1

A poor early-life diet creates a systemic state characterized by heightened inflammation, as well as leptin and glucocorticoid concentrations. These factors converge to induce epigenetic modifications that disrupt neuronal development and function, ultimately compromising cognitive performance.