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. 2017 Mar 13;8:272. doi: 10.3389/fimmu.2017.00272

Figure 1.

Figure 1

Perturbations of the three monocyte subsets in HIV-1-infected individuals. (A) The gating strategy for analysis of classical CD14++CD16−, intermediate CD14++CD16+, and non-classical CD14+CD16++ monocyte subsets is indicated. Frequencies of CD14+CD16++ (B), CD14++CD16+ (C), and CD14++CD16− (D) monocytes were analyzed by flow cytometry in healthy controls (HC), the patients with acute HIV-1 infection (AHI), chronic HIV-1-infected cART-naïve patients (CHI&ART-), and chronic HIV-1-infected patients with undetectable viral load after cART (CHI&ART+). All p values were calculated using an ANOVA, Student’s t-test, or the Mann–Whitney U test, *p < 0.05, **p < 0.01. Correlations between the frequency of the CD14++CD16+ monocytes and CD4 T cell counts (E) as well as the CD4/CD8 ratio (F) calculated by the Spearman correlation test (HC, AHI, CHI&ART−, and CHI&ART+ groups).