Figure 2. Downregulated ELF5 Increases the development of LNCaP Xenograft.

shScr or shELF5 infected LNCaP cells were injected subcutaneously into NOD-SCID mice, with 8 mice per group. (A,B) The mean tumor volume and the distribution of individual weight are shown. *P < 0.05. (C) Mice were sacrificed at eight weeks post implantation. The tumor samples, BrdU stain, TUNEL stain and the quantity analyses are shown. All images were collected at the same magnification.