Table 2.
Frequency of Retinal Toxicity in Different Groups
| Variable |
Retinal Toxicity
|
P Value | |
|---|---|---|---|
| No | Yes | ||
| Sex | 0.514 | ||
| Men | 4 (80) | 1 (20) | |
| Women | 38 (68.5) | 17 (31.5) | |
| Age, Y | 0.006 | ||
| <40 | 25 (86.2) | 4 (13.8) | |
| ≥40 | 16 (53.3) | 14 (46.7) | |
| Type of Rheumatic Disease | 0.539 | ||
| Rheumatoid Arthritis | 25 (69.4) | 11 (30.6) | |
| Systemic Lupus Erythematosus | 10 (62.5) | 6 (37.5) | |
| Other | 6 (85.7) | 1 (14.3) | |
| Daily HCQ Dose, mg | 0.062 | ||
| <200 | 30 (63.8) | 17 (36.2) | |
| ≥200 | 11 (91.7) | 1 (8.3) | |
| Cumulative HCQ Dose, mg | 0.002 | ||
| <100 | 25 (92.6) | 2 (7.4) | |
| 100-199 | 5 (55.6) | 4 (44.4) | |
| ≥200 | 11 (47.8) | 12 (52.2) | |
| Duration of HCQ Use, mo | 29.3 ± 21.5 | 75.2 ± 45.1 | < 0.001 |
a
Abbreviations: HCQ, hydroxychloroquine.
b
Data are presented as No. (%) or Mean ± SD.