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Superimposed catalytic cores of AChE (blue) and Cdc25A (red). The best matching parts were aligned with an rms deviation of 2.74 Å at an alignment length of 49 residues. The sequence identities in this best matching part amount to 8.2%. Also shown, in Corey–Pauling–Koltun (CPK) representation, are the catalytic residues, Ser-200 and Cys-430. They share the same location.
