TABLE 2 .
Relative fold changes of P. aeruginosa LESB58 mRNA transcripts from abscesses 3 days postinfectiona
| Gene | Description | Function or product | Fold changeb |
|---|---|---|---|
| pvdE (PA2397) | Pyoverdine siderophore ABC transporter | Iron uptake | 124.8 |
| toxA (PA1148) | Exotoxin A type II secretion system substrate | Exotoxin A | 24.9 |
| wzz (PA3160) | Lipopolysaccharide (LPS) O-antigen chain length regulator | Surface LPS | 24.4 |
| fimT (PA4549) | Type 4 pilus biogenesis protein | Adherence | 17.9 |
| lipC (PA4813) | Lipase type II secretion system substrate | Lipase C | 13.2 |
| lipA (PA2862) | Major lipase type II secretion system substrate | Lipase A | 10.4 |
| chpE (PA0417) | Probable chemotaxis protein | Chemotaxis | 8.2 |
| pchB (PA4230) | Pyochelin siderophore biosynthesis | Iron uptake | 8.2 |
| exsA (PA1713) | Type III secretion transcriptional activator | Type III secretion | 8.0 |
| mucC (PA0765) | Positive regulator for alginate biosynthesis | Exopolysaccharide | 6.8 |
| fliI (PA1104) | Flagellum-specific ATP synthase | Motility | 5.4 |
| pslD (PA2234) | Psl exopolysaccharide biosynthesis | Biofilm matrix | 5.4 |
| relA (PA0934) | Stringent stress response mediator ppGpp synthesis | Stringent response | 1.2 |
| nirQ (PA0520) | Denitrification regulatory protein | N metabolism | −1.2 |
| algR (PA5261) | Global two-component response regulator | Regulator | −1.6 |
| lasR (PA1430) | Transcriptional regulator for LasRI system | Quorum sensing | −2.0 |
| pscI (PA1722) | Type III secretion export protein | Type III secretion | −2.5 |
| rhlB (PA3478) | Rhamnolipid rhamnosyltransferase chain B | Biosurfactant | −2.6 |
| lasB (PA3724) | Elastase type II secretion system substrate | Elastase | −2.9 |
| rhlR (PA3477) | Transcriptional regulator for RhlRI system | Quorum sensing | −6.9 |
| phzA2 (PA1899) | Phenazine biosynthesis | Phenazine | −12.8 |
| gacA (PA2586) | Two-component system response regulator | Global activator | −14.6 |
a
Transcript abundance was determined by quantitative RT-PCR. Data represent the means of results from at least 3 replicates.
b
Data represent fold changes compared to cells grown in LB medium.