Fig. S2.

Statistical analysis of simulated hydrogen-bonding RDFs that are presented in Fig. 4 B and C. All curves present results for the CHARMM peptide model. With the exception of the osmotic TIP3P curve, which corresponds to simulations with the TIP3P water model, all curves present results with the SPC/E water model. The colored curves present the simulated RDFs, whereas the black bands indicate estimates of the simulated uncertainty. In each case, the statistical uncertainty is obtained as the SE obtained from splitting the simulation trajectory into blocks of 10-ns duration.