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. 2016 Jun 15;7(50):82139–82157. doi: 10.18632/oncotarget.10080

Table 3. The five-year overall survival on different clinicopathological factors was used Kaplan Meier and univariate analysis.

Variable 5-OS (%) log-rank test P-value Univariate analysis
HR 95%CI
Sex 0.345
 male 74.1 1
 female 53.3 1.445 0.670-3.114
Age 0.611
 ≤64y 64.0 1
 >64y 49.5 1.218 0.569-2.606
IASLC/ATS/ERS classification risk group (predominant adenocarcinoma) 0.037
 high risk 42.1 1
 middle risk 61.3 0.470 0.204-1.082
 low risk 75.0 0.250 0.053-1.188
Differentiation 0.001
 poor 26.0 1
 moderate 49.0 0.951 0.393-2.301
 well 79.4 0.238 0.092-0.619
Pleural invasion 0.744
 present 64.7 1
 absent 60.3 0.882 0.414-1.879
Distant metastases 0.066
 without 69.1 1
 with 50.0 5.404 0.717-40.723
Lymph node metastasis 0.008
 without 49.7 1
 with 49.1 2.711 1.263-5.822
T states 0.101
 T3/T4 33.3 1
 T2 58.9 0.262 0.087-0.791
 T1 68.0 0.226 0.067-0.762
TNM Stage <0.001
 I/II 65.0 1
 III/IV 23.7 4.538 2.076-9.920
Operation mode 0.933
 wedge resection 73.3 1
 lobectomy/other 54.7 1.047 0.362-3.027
Concentration of CEA (ug/l) 0.045
 <5 60.6 1
 ≥5 61.7 2.185 0.998-4.780
YBX1 0.044
 low 74.9 1
 high 40.5 2.111 1.003-4.444
CDC25a 0.004
 low 79.7 1
 high 45.5 3.124 1.370-7.123

Note:

Abbreviations: 5-OS, five-year overall survival; CEA, carcino-embryonic antigen.