Table 2. Effects of DS treatment with or without Cu on human primary adult B-ALL cells (n=32) and normal PBMCs (n=9).
| DS (μM) | 0 | 0 | 0.025 | 0.05 | 0.10 | 0.20 | P- value |
|---|---|---|---|---|---|---|---|
| Cu (μM) | 0 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | |
| Primary B-ALL cells | 37.36±17.49 | 38.65±18.68 | 44.52±18.84 | 57.50±22.87 | 66.88±21.68 | 73.37±19.20 | 0.000 |
| Normal PBMCs | 19.57±7.40 | 17.87±7.14 | 20.89±8.22 | 23.04±6.18 | 24.76±6.57 | 26.82±8.26 | 0.117 |
Primary B-ALL cells and normal PBMCs were incubated with the indicated doses of DS in the presence or absence of Cu for 24hr, after which percentage of apoptotic cells were assessed by flow cytometry. Values represent mean ± SD for at least three independent experiments.