Table 1. The demographic and clinicopathologic characteristics of the patients with pancreatic ductal adenocarcinoma treated by surgical resection.
| Characteristics | Patients for the miRNA microarray | Patients of the evaluation cohort (n) |
||
|---|---|---|---|---|
| Good prognosis group | Poor prognosis group | P value | ||
| No. Patients | 10 | 10 | 114 | |
| Age (years) < 60 | 4 | 6 | 0.371 | 55 (48.2%) |
| ≥ 60 | 6 | 4 | 59 (51.8%) | |
| Gender Male | 4 | 6 | 0.371 | 68 (59.6%) |
| Female | 6 | 4 | 46 (40.4%) | |
| Location of tumor Head | 8 | 9 | 0.500 | 88 (77.2%) |
| Body or tail | 2 | 1 | 26 (22.8%) | |
| Type of operation Pancreaticoduodenectomy | 8 | 8 | 0.709 | 88 (77.2%) |
| Distal pancreatectomy | 2 | 2 | 25 (21.9%) | |
| Total pancreatectomy | 0 | 0 | 1 (0.9%) | |
| Maximum tumor diameter (mean ± SD) (cm) | 4.35 ± 1.23 | 4.75 ± 1.44 | 0.512 | 4.22 ± 1.81 |
| Differenciation Well | 4 | 3 | 0.881 | 40 (35.1%) |
| Moderately | 4 | 5 | 57 (50.0%) | |
| Poor | 2 | 2 | 17 (14.9%) | |
| Surgical margins Negative | 9 | 10 | 0.500 | 111 (97.4%) |
| Positive | 1 | 0 | 3 (2.6%) | |
| pT category pT1+ pT2 | 4 | 3 | 0.500 | 58 (50.9%) |
| pT3+pT4 | 6 | 7 | 56 (49.1%) | |
| pN category pN0 | 4 | 4 | 0.675 | 84 (73.7%) |
| pN1 | 6 | 6 | 30 (26.3%) | |
| Vessel invasion No | 5 | 3 | 0.325 | 61 (53.5%) |
| Yes | 5 | 7 | 53 (46.5%) | |
| Vascular tumor thrombus No | 10 | 10 | --- | 111 (97.4%) |
| Yes | 0 | 0 | 3 (2.6%) | |
| Adjacent organs invasion No | 7 | 8 | 0.500 | 86 (75.4%) |
| Yes | 3 | 2 | 28 (24.6%) | |
| pTNM category I | 0 | 0 | 0.675 | 53 (46.4%) |
| IIA | 4 | 4 | 15 (13.2%) | |
| IIB | 6 | 6 | 18 (15.8%) | |
| III | 0 | 0 | 28 (24.6%) | |
| CA19-9 (median, range) (U/mL) | 250.0 (9.69–739.70) |
130.40 (0.6–1551) |
0.791 | 287.61 (0.60–12076.00) |