Table 3. Relationship between the expression of miR-891b and clinicopathologic characteristics in patients with pancreatic ductal adenocarcinoma patients treated by surgical resection.
Characteristics | miR-891b high expression (n,%) | miR-891b low expression (n,%) | P value |
---|---|---|---|
Age (years) < 60 | 27(48.2) | 28(48.3) | 0.995 |
≥ 60 | 29(51.8) | 30(51.7) | |
Gender Male | 37(66.1) | 31(53.4) | 0.170 |
Female | 19(33.9) | 27(46.6) | |
Location of tumor Head | 46(82.1) | 42(72.4) | 0.216 |
Body or tail | 10(17.9) | 16(27.6) | |
Type of operation Pancreaticoduodenectomy | 47(83.9) | 41(70.7) | 0.189 |
Distal pancreatectomy | 9(16.1) | 16(27.6) | |
Total pancreatectomy | 0(0) | 1(1.7) | |
Maximum tumor diameter (cm) (mean ± SD) | 3.83 ± 1.50 | 4.58 ± 2.00 | 0.027 |
Differenciation Well | 19(33.9) | 21(36.2) | 0.373 |
Moderately | 31(55.4) | 26(44.8) | |
Poor | 6(10.7) | 11(19.0) | |
Surgical margins Negative | 53(94.6) | 58(100) | 0.115 |
Positive | 3(5.4) | 0(0) | |
pT category pT1+ pT2 | 34(60.7) | 24(41.4) | 0.039 |
pT3+pT4 | 22(39.3) | 34(58.6) | |
pN category pN0 | 51(91.1) | 33(56.9) | 0.000 |
pN1 | 5(8.9) | 25(43.1) | |
Vessel invasion No | 34(60.7) | 27(46.6) | 0.130 |
Yes | 22(39.3) | 31(53.4) | |
Vascular tumor thrombus No | 56(100.0) | 55(94.8) | 0.244 |
Yes | 0(0.0) | 3(5.2) | |
Adjacent organs invasion No | 44(78.6) | 42(72.4) | 0.445 |
Yes | 12(21.4) | 16(27.6) | |
pTNM category I | 33(58.9) | 20(34.5) | 0.015 |
II | 10(17.9) | 23(39.7) | |
III | 13(23.2) | 15(25.9) | |
CA19-9 (U/mL) < 37.0 | 7(14.9) | 8(15.1) | 0.978 |
≥ 37.0 | 40(85.1) | 45(84.9) |
Abbreviations: pT: pathologic T; pN: pathologic N; pTNM: pathologic TNM.