Figure 1. Effects of hyperin on histopathological changes in kidney tissues in LPS-induced AKI mice.
Hhyperin (25, 50, 100 mg/kg) were given intraperitoneally (i.p.) 1 h after LPS treatment. 24 h after LPS challenge, Kidney tissues from each experimental group were processed for histological evaluation. Representative histological changes of kidney obtained from mice of different groups. (A) Control group, (B) LPS group, (C) LPS+ hyperin (25 mg/kg) group, (D) LPS+ hyperin (50 mg/kg) group, (E) LPS + hyperin (100 mg/kg) group (Hematoxylin and eosin staining, magnification 200×).