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. 2016 Nov 2;7(50):82620–82633. doi: 10.18632/oncotarget.13012

Figure 1. LncRNA PVT1 is overexpressed in osteosarcoma and decreases the survival rate of osteosarcoma patients.

Figure 1

(A) The mRNA expression level of PVT1 was measured by qRT-PCR in osteosarcoma tissues (n = 26) and corresponding noncancerous tissues (n = 26). (B) The mRNA expression level of PVT1 was measured by qRT-PCR in the normal osteoblast cell line NHost and various osteosarcoma cell lines (KHOS, 143b, LM7, U2OS, and MG-63) (*P < 0.05). (C) Comparison of survival curves between tumors expressing high levels of PVT1 (n =29) and tumors expressing low levels of PVT (n = 24). (D) qRT-PCR was used to measure the mRNA expression level of PVT1 in metastatic osteosarcoma tissues (n = 13) and primary osteosarcoma tissues (n = 13).