Table 2. miR-195 directly targets summered by oncomiRDB.
pubmedID | tissue | miRNAs | direct_targets | miRNA_function | sum_effect |
---|---|---|---|---|---|
23162665 | bone and muscle | miR-195 | FASN(2194) | decrease cell migration decrease cell invasion | tumor-suppressive |
22888524 | liver | miR-195 | LATS2(26524) | increase apoptosis | tumor-suppressive |
22289176 | bladder | miR-195 | CDK4(1019) | induce cell cycle G1 arrest inhibit cell growth | tumor-suppressive |
22217655 | brain | miR-195 | NPA | inhibit cell cycle progression inhibit cell invasion | tumor-suppressive |
21947305 | liver | miR-195 | BCL2L2(599) | reduce 5-FU resistance | NPA |
21350001 | breast | miR-195 | CCND1(595) RAF1(5894) | reduce cell proliferation reduce cell invasion | tumor-suppressive |
20727858 | colorectum | miR-195 | BCL2(596) | reduce cell viability promote cell apoptosis suppress tumorigenicity | tumor-suppressive |
19441017 | liver | miR-195 | CCND1(595) CDK6(1021) E2F3(1871) | inhibit cell cycle G1/S transition inhibit colony formation | tumor-suppressive |