Table 2. Allele and genotype distributions of SNPs in TERT and their associations with risk of gastric cancer.
| SNP | Sample | Genotype distribution n | p# | Allele distribution | OR (95% CI) | p# | HWE p-value | |||
|---|---|---|---|---|---|---|---|---|---|---|
| rs10069690 | TT | TC | CC | T | C | |||||
| case | 18 | 89 | 195 | 0.021* | 125 | 479 | 1.56 (1.15–2.11) | 0.004* | ||
| control | 8 | 69 | 219 | 85 | 507 | 0.347 | ||||
| rs2242652 | AA | AG | GG | A | G | |||||
| case | 17 | 95 | 190 | 0.066 | 129 | 475 | 1.43 (1.06–1.91) | 0.017* | ||
| control | 9 | 78 | 213 | 96 | 504 | 0.523 | ||||
| rs2853677 | GG | GA | AA | G | A | |||||
| case | 97 | 217 | 173 | 0.171 | 231 | 373 | 1.25 (0.99–1.58) | 0.066 | ||
| control | 106 | 252 | 144 | 199 | 401 | 0.696 | ||||
| rs2853676 | TT | TC | CC | T | C | |||||
| case | 16 | 100 | 186 | 0.006* | 132 | 472 | 1.63 (1.21–2.19) | 0.001* | ||
| control | 7 | 74 | 219 | 88 | 512 | 0.817 | ||||
SNP single nucleotide polymorphism, OR odds ratio, 95% CI 95% confidence interval, HWE Hardy–Weinberg equilibrium.
P# value from were calculated from two-sided Chi-squared test.
p* ≤ 0.05 indicates statistical significance.