Table 3. Frequency distributions of prominent SNPs and their associations with the risk of gastric cancer.
| SNP | Minor allele | MAF | Dominant model | Recessive model | Additive model | ||||
|---|---|---|---|---|---|---|---|---|---|
| Case | Control | OR (95% CI) | p# | OR (95% CI) | p# | OR (95% CI) | p# | ||
| rs10069690 | T | 0.207 | 0.144 | 1.67 (1.16–2.4) | 0.006* | 2.62 (1.08–6.34) | 0.033* | 1.61 (1.19–2.18) | 0.002* |
| rs2242652 | A | 0.214 | 0.160 | 1.49 (1.05–2.12) | 0.026* | 2.32 (0.98–5.49) | 0.054 | 1.47 (1.09–1.97) | 0.011 |
| rs2853677 | G | 0.382 | 0.332 | 1.34 (0.96–1.88) | 0.089 | 1.27 (0.76–2.12) | 0.356 | 1.24 (0.97–1.59) | 0.088 |
| rs2853676 | T | 0.219 | 0.147 | 1.72 (1.2–2.45) | 0.003* | 2.26 (0.89–5.73) | 0.085 | 1.63 (1.2–2.21) | 0.002* |
p# values were calculated by unconditional logistic regression.
p* ≤ 0.05 indicates statistical significance.