Table 1. Multivariate analysis of prognostic factors for overall survival in the entire patient cohort and the female, non-smoker, ADC subgroup.
| Variable | Category | Total group (n=446) | Female, non-smoker, and ADC (n=68) | ||||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | ||
| Sex | Male/Female | 1.645 | 0.943-2.870 | 0.080 | - | - | - |
| Age group | ≥65 yr/<65 yr | 1.637 | 1.231-2.177 | <0.01 | 2.598 | 0.829-8.136 | 0.101 |
| Smoking | Smoker/Non-smoker | 1.336 | 0.862-2.070 | 0.195 | - | - | - |
| Histology | SCC/ADC | 1.580 | 1.140-2.191 | 0.006 | - | - | - |
| Stage | III/I+II | 2.436 | 1.709-3.473 | <0.01 | 7.755 | 1.497-10.16 | 0.015 |
| LYN | Positive/Negative | 1.602 | 1.062-3.419 | 0.025 | 3.449 | 1.182-8.065 | 0.023 |
SCC, squamous cell carcinoma; ADC, adenocarcinoma; HR, hazard ratio; CI, confidence interval; P, p-value