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. 2016 Oct 17;7(50):82943–82952. doi: 10.18632/oncotarget.12705

Table 2. Summary of NGS ALK fusion detection and FISH patterns.

FISH PATTERN NEXT GENERATION SEQUENCING
POSITIVE FOR EML4-ALK FUSION POSITIVE FOR ALK FUSION BY 3′/5' READ RATIO ONLY NEGATIVE TOTAL POSITIVE
Split signal (N=15) 10
(67%)
2
(13%)
3
(20%)
12
(80%)
Single orange
(N=10)
2
(20%)
2
(20%)
6
(60%)
4
(40%)
Mixed pattern (N=3) 0
(0%)
0
(0%)
3
(100%)
0
(0%)