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. 2016 Oct 15;7(50):82972–82984. doi: 10.18632/oncotarget.12690

Table 3. Prognostic factors for lung SCC patients.

Variables HR Univariate 95% CI P HR§ Multivariate 95% CI P§
OS
Age (years)
 ≤55 vs. >55 1.009 0.962-1.058 0.712
Gender
 Male vs. female 0.563 0.171-1.855 0.345
Differentiation
 Well/moderate vs poor 1.442 0.716-2.903 0.306
pT status
 pT2-4 vs pT1 1.806 1.089-2.996 0.022 0.824
Lymph node metastasis
 Positive vs. Negative 1.884 1.238-2.865 0.003 0.463
pTNM stage
 II-III vs. I 2.070 1.446-2.962 0.000 1.878 1.026-3.438 0.041
14-3-3ζ expression
 low vs. high 4.827 1.966-11.854 0.001 8.358 3.120-22.391 0.000
TGFβR1 expression
 low vs. high 0.415 0.197-0.874 0.021 0.219 0.092-0.521 0.001
pSMAD3 expression
 low vs. high 0.671 0.307-1.466 0.317

CI, confidence interval; HR, hazard ratio; OS, overall survival.