Table 3. Prognostic factors for lung SCC patients.
Variables | HR | Univariate 95% CI | P | HR§ | Multivariate 95% CI | P§ |
---|---|---|---|---|---|---|
OS | ||||||
Age (years) | ||||||
≤55 vs. >55 | 1.009 | 0.962-1.058 | 0.712 | |||
Gender | ||||||
Male vs. female | 0.563 | 0.171-1.855 | 0.345 | |||
Differentiation | ||||||
Well/moderate vs poor | 1.442 | 0.716-2.903 | 0.306 | |||
pT status | ||||||
pT2-4 vs pT1 | 1.806 | 1.089-2.996 | 0.022 | 0.824 | ||
Lymph node metastasis | ||||||
Positive vs. Negative | 1.884 | 1.238-2.865 | 0.003 | 0.463 | ||
pTNM stage | ||||||
II-III vs. I | 2.070 | 1.446-2.962 | 0.000 | 1.878 | 1.026-3.438 | 0.041 |
14-3-3ζ expression | ||||||
low vs. high | 4.827 | 1.966-11.854 | 0.001 | 8.358 | 3.120-22.391 | 0.000 |
TGFβR1 expression | ||||||
low vs. high | 0.415 | 0.197-0.874 | 0.021 | 0.219 | 0.092-0.521 | 0.001 |
pSMAD3 expression | ||||||
low vs. high | 0.671 | 0.307-1.466 | 0.317 |
CI, confidence interval; HR, hazard ratio; OS, overall survival.