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. 2016 Nov 15;7(50):83040–83050. doi: 10.18632/oncotarget.13349

Figure 5. Protection from leukemic death by ZF1 in vivo.

Figure 5

(A) Kaplan-Meier plots of overall survival for BALB/c nude mice engrafted with CCRF cells for ALL (Left) and U937 cells for AML (Right) in the presence of anti-CD47 antibodies (ZF1 and B6H12). ① Pretreatment with cyclophosphamide. ② Inoculation of Leukemia cell. ③ Start administration. ④ Stop administration. (B). Flow cytometry analysis of peripheral blood from leukemic cells-engrafted mouse models for the presence of leukemic cells (human CD45+) after anti-CD47 antibody treatment.