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. 2016 Nov 4;7(50):83115–83133. doi: 10.18632/oncotarget.13073

Figure 7. Genomic alterations of genes in the MUC1 network.

Figure 7

The MUC1 network (see Supplementary Figure S4 and Supplementary Table S2 for details) was analyzed for genomic alterations using the 3 largest and representative prostate cancer datasets within the cBioPortal database [44, 45]. These datasets were deposited from studies as a result of their publications [4648], and cover 333 primary PCs [46], 150 metastatic PCs [47], and 107 CRPCs derived from 77 patients [48]. A. Analyses were performed using the tools provided by cBioPortal [44, 45]. For the primary and metastatic population, only a proportion of cohorts containing the tumors with the relevant genomic alterations are included. Each column represents an individual tumor; red and blue slots are for gene amplification and deep deletion, respectively. Gene names and their rates of alteration are shown on the left and right of individual rows, respectively. B. Summary of genomic alterations in the MUC1 network in the primary, metastatic and castration resistant PC cohort.