Table 2. Nanostring analysis of gene expression in primary prostate cancer tissues.
| Genes | P1a | P2a | P3a | P4a | P5a | P6a | P7a |
|---|---|---|---|---|---|---|---|
| MUC1 | +2 | +2.4 | Nc | +3.1 | N | +1.4 | N |
| TMPRSS2-ERGb | +16.2 | +30.2 | N | N | +17 | +25.3 | +27.3 |
| PTENb | −1.4 | −1.4 | N | N | −1.4 | −1.3 | −2.6 |
a
patients 1-3 (GS6), patients 4-6 (GS7, 4+3 for P4,5, and 3+4 for P6), and P7 (GS4+4).
b
TRPRSS2-ERG and PTEN were used as positive controls for upregulated and downregulated genes in PC.
c
no downregulation or upregulation
Student's t-test (2-tails) was used to determine the p-values for changes in MUC1 (p=0.044), PTEN (p=0.051), and ERG (p=0.004).